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Evaluation of feline immunodeficiency virus ORF-A mutants as candidate attenuated vaccine

✍ Scribed by M. Pistello; F. Bonci; P. Isola; P. Mazzetti; A. Merico; L. Zaccaro; D. Matteucci; M. Bendinelli

Book ID: 113946240
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 704 KB
Volume: 332
Category: Article
ISSN: 0042-6822
DOI: 10.1016/j.virol.2004.12.004

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## Abstract A temperature‐sensitive mutant virus unable to replicate at 38°C was recovered from passage 189 (IVpi‐189) of Madin‐Darby canine kidney cells infected persistently with influenza A. Immunofluorescent staining of the IVpi‐189 virus‐infected cells revealed disrupted transport of the matri