Evaluation of diffusion-weighted imaging for the differential diagnosis of poorly contrast-enhanced and T2-prolonged bone masses: Initial experience
✍ Scribed by Yoshiko Hayashida; Toshinori Hirai; Toshitake Yakushiji; Kazuhiro Katahira; Osamu Shimomura; Masanori Imuta; Takeshi Nakaura; Daisuke Utsunomiya; Kazuo Awai; Yasuyuki Yamashita
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 600 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To determine whether quantitative diffusion‐weighted imaging (DWI) is useful for characterizing poorly contrast‐enhanced and T2‐prolonged bone masses.
Materials and Methods
We studied 20 bone masses that showed high signal intensity on T2‐weighted images and poor enhancement on contrast‐enhanced T1‐weighted images. These included eight solitary bone cysts, five fibrous dysplasias, and seven chondrosarcomas. To analyze diffusion changes we calculated the apparent diffusion coefficient (ADC) for each lesion.
Results
The ADC values of the two types of benign lesions and chondrosarcomas were not significantly different. However, the mean ADC value of solitary bone cysts (mean ±SD, 2.57 ± 0.13 × 10^–3^ mm^2^/second) was significantly higher than that of fibrous dysplasias and chondrosarcomas (2.0 ± 0.21 × 10^–3^ mm^2^/second and 2.29 ± 0.14 × 10^–3^ mm^2^/second, respectively, P < 0.05). None of the lesions with ADC values lower than 2.0 × 10^–3^ mm^2^/second were chondrosarcomas.
Conclusion
Although there was some overlapping in the ADC values of chondrosarcomas, solitary bone cyst, and fibrous dysplasia, quantitative DWI may aid in the differential diagnosis of poorly contrast‐enhanced and T2‐prolonged bone masses. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.