Evaluation of different indirect measure
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L. F. Lacey; O. N. Keene; C. Duquesnoy; A. Bye
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Article
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1994
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John Wiley and Sons
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English
โ 414 KB
As indirect measures of rate of drug absorption (metrics), maximum plasma concentration (C-) is confounded by extent of drug absorption and the time to reach C , , (t-) is a discrete variable, dependent on blood sampling frequency. Building on the work of Endrenyi et al., we have compared different