Des-y-carboxy prothrombin [DCP], a protein induced by vitamin K absence or antagonist-I1 and also abbreviated PIVKA-11, was evaluated as a serologic marker for hepatocellular carcinoma (HCC). Its plasma levels were measured by enzyme immunoassay (E-1023) using an anti-DCP monoclonal antibody in 514
Evaluation of des-γ-carboxy prothrombin as a marker protein of hepatocellular carcinoma
✍ Scribed by Yoshihiro Deyashiki; Yoshimi Nishioka; Katsumi Takahashi; Yoshitane Kosaka; Koji Suzuki
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 455 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND Des‐γ‐carboxy prothrombin (DCP) has been reported to be an important prognostic factor in patients with hepatocellular carcinoma (HCC). Recently, a monoclonal antibody, 19B7, which recognizes the Gla domain of DCP, has been identified. The 19B7 antibody recognizes an epit
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## Background: Measurements of serum concentrations of des-gamma-carboxy prothrombin (dcp) are widely used for diagnosing hepatocellular carcinoma (hcc). however, the dcp is not always sensitive enough to detect small hccs. in the current study, the authors investigated the usefulness of dcp in the