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Evaluation of death pathway genes FAS and FASL polymorphisms in chronic HBV infection

โœ Scribed by Zamani, A. G.; Barlas, I. O.; Durakbasi-Dursun, G.; Ural, O.; Erdal, E.; Yildirim, M. S.

Book ID
120583796
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
103 KB
Volume
40
Category
Article
ISSN
1744-3121

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## Abstract The FAS receptor/ligand system is a key regulator of apoptotic cell death and corruption of this signaling pathway has been shown to participate in carcinogenesis. Functional polymorphisms in the FAS (FAS โˆ’1377G/A) and FASL (FASL โˆ’844T/C) genes alter their transcriptional activity. Ther