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Evaluation of cytotoxic and genotoxic effects of two resin-based root-canal sealers and their components on human leucocytes in vitro

✍ Scribed by A. Baraba; D. Želježić; N. Kopjar; M. Mladinić; I. Anić; I. Miletić

Book ID: 108784946
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 198 KB
Volume: 44
Category: Article
ISSN: 0143-2885
DOI: 10.1111/j.1365-2591.2011.01869.x

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## Abstract Cyclooxygenase‐2 (COX‐2) is an inducible enzyme believed to be responsible for prostaglandin synthesis at site of inflammation. Recently, the activation of COX‐2 expression may be one of the important pathogenesis of root‐canal‐sealers–induced periapical inflammation. However, little is