Evaluation of creams and ointments as suitable formulations for peldesine
β Scribed by Tacey X Viegas; Lise L Van Winkle; Paul A Lehman; Sue F Franz; Thomas J Franz
- Book ID
- 108453973
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 93 KB
- Volume
- 219
- Category
- Article
- ISSN
- 0378-5173
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A procedure was developed for the in vivo evaluation of the bioavailability of topical formulations containing a limited amount of the active drug product estimated as the rate and extent to which the drug i s released from the vehicle to the skin. It i s assumed that drug transfer follows Fick's la
## Abstract ## Objective The Disease Activity Score (DAS) is widely used in clinical trials. A DAS of 5.1 defines the level of severe rheumatoid arthritis (RA) and is the criterion for the initiation of antiβtumor necrosis factor therapy in the UK and The Netherlands. In North America, similar rul