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Evaluation of classical complement pathway activation in rheumatoid arthritis: Measurement of C1q–C4 complexes as novel activation products

✍ Scribed by Diana Wouters; Alexandre E. Voskuyl; Esmeralda T. H. Molenaar; Ben A. C. Dijkmans; C. Erik Hack


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
89 KB
Volume
54
Category
Article
ISSN
0004-3591

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The activation of C1 by circulating immune complexes in patients with rheumatoid arthritis was investigated. C1rC1s(C1-In)2 complexes in EDTA-plasma, reflecting C1 activation in vivo, were slightly raised in 35 of 57 patients with rheumatoid arthritis, though most patients had elevated levels of cir