## Abstract CD44 core and splice variant exon expression was investigated in the stratified transitional epithelium of the urinary tract and in normal and malignant bladder epithelial cell lines __in vitro.__ Antibodies against core CD44 epitopes and splice exon variants v3, v4/5, v5 and v6 showed
Evaluation of CD44 transcription variants in human digestive tract carcinomas and normal tissues
β Scribed by Koichiro Higashikawa; Hiroshi Yokozaki; Teruyoshi Ue; Kiyomi Taniyama; Takenori Ishikawa; David Tarin; Eiichi Tahara
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- French
- Weight
- 818 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
β¦ Synopsis
We generated DNA probes for CD44 variable region exons I I (v6) to 14 (v9) and also for intronic sequences and examined the expression of aberrant CD44 transcripts in digestive tract carcinomas, colorectal adenomas and intestinal metaplasia of the stomach. The study used the reverse transcriptionpolymerase chain reaction/Southern blot technique.
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