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Evaluation of BTS 67 582, a novel antidiabetic agent, in normal and diabetic rats

✍ Scribed by R B Jones; K Dickinson; D M Anthony; A R Marita; C L Kaul; W R Buckett


Book ID
110002816
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
356 KB
Volume
120
Category
Article
ISSN
0007-1188

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Investigation of the effects of BTS 67 5
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BTS 67 582 stimulates insulin release and causes dose-dependent glucose-lowering activity in the conscious beagle dog. Plasma glucose levels were lowered within 1 h and were maximally reduced by 53.2 Β± 2.7% 2-3 h after oral dosing with 90 Β΅mol/kg BTS 67 582 (equivalent to 22.5 mg/kg as the free base