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Evaluation of brain inflammation and cognitive abilities in the mouse model of MPS IIIC

✍ Scribed by Martins, Carla; Dormoy-Raclet, Virginie; Bruno, Luigi; Dridi, Larbi; Di Cristo, Graziella; Hamel, Edith; Pshezhetsky, Alexey

Book ID
122510870
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
66 KB
Volume
108
Category
Article
ISSN
1096-7192

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## Abstract Mucopolysaccharidosis (MPS) IIIB is a lysosomal storage disease with severe neurological manifestations due to α‐__N__‐acetylglucosaminidase (NaGlu) deficiency. The mechanism of neuropathology in MPS IIIB is unclear. This study investigates the role of immune responses in neurological d