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Evaluation of Bioanalytical Assays for Toxicity Assessment and Mode of Toxic Action Classification of Reactive Chemicals

✍ Scribed by Harder, Angela; Escher, Beate I.; Landini, Paolo; Tobler, Nicole B.; Schwarzenbach, René P.

Book ID
121717419
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
137 KB
Volume
37
Category
Article
ISSN
0013-936X

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## Abstract This article reviews the mechanistic basis of the tissue residue approach for toxicity assessment (TRA). The tissue residue approach implies that whole‐body or organ concentrations (residues) are a better dose metric for describing toxicity to aquatic organisms than is the aqueous conce