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Evaluation of behavior and neuropeptide markers of pain in a simple, sciatic nerve-pinch pain model in rats

✍ Scribed by Kazutoshi Hirose; Nahoko Iwakura; Sumihisa Orita; Masaomi Yamashita; Gen Inoue; Kazuyo Yamauchi; Yawara Eguchi; Nobuyasu Ochiai; Shunji Kishida; Junichi Nakamura; Masashi Takaso; Tetsuhiro Ishikawa; Gen Arai; Masayuki Miyagi; Hiroto Kamoda; Yasuchika Aoki; Ryo Hiwatari; Jun Kakizaki; Toshikazu Kunishi; Motoaki Kono; Takane Suzuki; Tomoaki Toyone; Kazuhisa Takahashi; Kazuki Kuniyoshi; Seiji Ohtori

Publisher
Springer
Year
2010
Tongue
English
Weight
419 KB
Volume
19
Category
Article
ISSN
0940-6719

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## Abstract Tetanic stimulation of the sciatic nerve (TSS) produces long‐lasting pain hypersensitivity in rats. Long‐term potentiation (LTP) of C‐ and A‐fiber‐evoked field potentials in the spinal cord has been explored as contributing to central sensitization in pain pathways. However, the periphe