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Evaluation of Antigen-Based Heteropolymer for Treatment of Systemic Lupus Erythematosus in a Nonhuman Primate Model

โœ Scribed by Steven E. Pincus; Nadya Lukacher; Nehal Mohamed; Muctarr Sesay; Roger Zabinski; Rose Ebelle; Lisa Duncan; Juan Li; Xun Chen; Wu Peng; Josaih Adaelu; Leslie Casey; James P. Porter; George Spitalny; Linda L. Nardone


Book ID
115593941
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
347 KB
Volume
105
Category
Article
ISSN
1090-2341

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Granzyme B is dispensable for immunologi
โœ Kareem L. Graham; Donna L. Thibault; Jonathan B. Steinman; Lance Okeke; Peter N. ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 246 KB ๐Ÿ‘ 2 views

## Abstract ## Objective Proteolytic autoantigen cleavage by the serine protease granzyme B has been implicated in the development of systemic autoimmune disease; however, there has been no conclusive demonstration of a pathogenic role for granzyme B in autoimmunity. In this study, we evaluated th