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Evaluation of animal models for predicting skin penetration in man*1

โœ Scribed by REIFENRATH, W

Book ID
124126091
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
601 KB
Volume
4
Category
Article
ISSN
0272-0590

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An evaluation of mathematical models for
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โœ Guoping Lian; Longjian Chen; Lujia Han ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 204 KB

A number of mathematical models have been proposed for predicting skin permeability, mostly empirical and very few are deterministic. Early empirical models use simple lipophilicity parameters. The recent trend is to use more complicated molecular structure descriptors. There has been much debate on