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Evaluation of an in-capillary approach for performing quantitative cytochrome P450 activity studies

✍ Scribed by R. Curcio; R. Nicoli; S. Rudaz; J.-L. Veuthey

Book ID: 105893679
Publisher: Springer
Year: 2010
Tongue: English
Weight: 254 KB
Volume: 398
Category: Article
ISSN: 1618-2650
DOI: 10.1007/s00216-010-4175-9

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## Abstract Cytochrome P450 enzymes are a family of heme‐containing proteins located throughout the body with roles in metabolism of endogenous and exogenous compounds. Among exogenous compounds, clinically relevant pharmaceutical agents are nearly all metabolized by P450 enzymes. However, the acti