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Evaluation of an antibody-based genotype classification of the platelet fibrinogen receptor (GPIIb/IIIa)

โœ Scribed by B. Schwippert-Houtermans; S. Strapatsakis; P. Roesen; D. Tschoepe


Book ID
102136437
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
141 KB
Volume
46
Category
Article
ISSN
0196-4763

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โœ Vassilios Tsikaris ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 454 KB

## Abstract Activation of the platelet surface receptor GPIIb/IIIa is the final pathway of platelet aggregation, regardless of the initiating stimulus. RGD analogues, peptidomimetics and monoclonal antibodies to GPIIb/IIIa have been developed targeting the blockage of the receptor and inhibition of