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Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs

✍ Scribed by Mark N. Prichard; Ravi Kaiwar; Winthrop T. Jackman; Debra C. Quenelle; Deborah J. Collins; Earl R. Kern; George M. Kemble; Richard R. Spaete

Book ID
116958013
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
173 KB
Volume
23
Category
Article
ISSN
0264-410X

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✍ Sandra L. Fowler; Christopher J. Harrison; Martin G. Myers; Lawrence R. Stanberr πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 574 KB

## Abstract Factors that influence the outcome of genital herpes simplex virus (HSV) infection were explored in a guinea pig model. The viral inoculum required to establish infection in 50% of animals (ID~50~) was similar for inbred (strain 2) and out‐bred (Hartley) guinea pigs. However, the viral