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Evaluation of acetylsalicylic acid esterase in aspirin metabolism. Interspecies comparison

✍ Scribed by Ann M. Morgan; Edward B. Truitt Jr.


Publisher
John Wiley and Sons
Year
1965
Tongue
English
Weight
638 KB
Volume
54
Category
Article
ISSN
0022-3549

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## Abstract **BACKGROUND:** Analysis of the literature for nonsteroidal anti‐inflammatory drugs (NSAIDs) suggests that a low incidence of developmental anomalies occurs in rats given NSAIDs on specific days during organogenesis. Aspirin (acetylsalicylic acid [ASA]), an irreversible cyclooxygenase 1