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Evaluation of a predictive in vitro Leydig cell assay for anti-androgenicity of phthalate esters in the rat

✍ Scribed by Balbuena, Pergentino; Campbell, Jerry; Clewell, Harvey J.; Clewell, Rebecca A.

Book ID
121891837
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
757 KB
Volume
27
Category
Article
ISSN
0887-2333

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Eight phthalate esters, with alcohol chain lengths of 1-11 carbon atoms and with various degrees of branching, were tested in vitro in the L5178Y mouse lymphoma mammalian cell mutation assay and in the Balb/3T3 cell transformation assay. The tests were performed as part of a voluntary testing agreem