✦ LIBER ✦

Evaluation of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine and its analogues as PET radioligands for imaging nicotinic acetylcholine receptors

✍ Scribed by LaVerne Brown; Svetlana Chefer; Olga Pavlova; D. Bruce Vaupel; Andrei O. Koren; Alane S. Kimes; Andrew G. Horti; Alexey G. Mukhin

Book ID: 111178536
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 490 KB
Volume: 91
Category: Article
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.2004.02762.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Radiosynthesis and evaluation of 5-(2-(4

Radiosynthesis and evaluation of 5-(2-(4-pyridinyl)vinyl)-6-chloro-3-(1-[11CH3]methyl-2-(S)-pyrrolidinylmethoxy)pyridine and its analogs, high affinity ligands for studying nicotinic acetylcholine receptors by positron emission tomography

✍ L. L. Brown; A. G. Mukhin; S. I. Chefer; O. Pavlova; A. O. Koren; A. S. Kimes; A 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 169 KB

Synthesis and Evaluation of a Novel Seri

Synthesis and Evaluation of a Novel Series of 2-Chloro-5-((1-methyl-2-( S )-pyrrolidinyl)methoxy)-3-(2-(4-pyridinyl)vinyl)pyridine Analogues as Potential Positron Emission Tomography Imaging Agents for Nicotinic Acetylcholine Receptors

✍ Brown, LaVerne L.; Kulkarni, Santosh; Pavlova, Olga A.; Koren, Andrei O.; Mukhin 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 102 KB

Novel Pyridyl Ring C5 Substituted Analog

Novel Pyridyl Ring C5 Substituted Analogues of Epibatidine and 3-(1-Methyl-2( S )- pyrrolidinylmethoxy)pyridine (A-84543) as Highly Selective Agents for Neuronal Nicotinic Acetylcholine Receptors Containing β2 Subunits

✍ Wei, Zhi-Liang; Xiao, Yingxian; Yuan, Hongbin; Baydyuk, Maryna; Petukhov, Pavel 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 131 KB

ChemInform Abstract: New Synthesis and E

ChemInform Abstract: New Synthesis and Evaluation of Enantiomers of 7-Methyl-2-exo-(3′-iodo-5′-pyridinyl)-7-azabicyclo[2.2.1]heptane as Stereoselective Ligands for PET Imaging of Nicotinic Acetylcholine Receptors.

✍ Yongjun Gao; Andrew G. Horti; Hiroto Kuwabara; Hayden T. Ravert; Daniel P. Holt; 📂 Article 📅 2009 🏛 John Wiley and Sons ⚖ 24 KB 👁 2 views

Efficient synthesis of 6-chloro-3-((2-(S

Efficient synthesis of 6-chloro-3-((2-(S)-azetidinyl)methoxy)-5-((E)-2-(2-[18F]fluoropyridin-4-yl)vinyl)pyridine ([18F]NIDA 52289), a very high affinity radioligand for nicotinic acetylcholine receptors

✍ Yi Zhang; Andrew W. Hall; Andrew G. Horti 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 113 KB

## Abstract 6‐Chloro‐3‐((2‐(__S__)‐azetidinyl)methoxy)‐5‐((__E__)‐2‐(2‐[^18^F]fluoropyridin‐4‐yl)vinyl)pyridine ([^18^F]NIDA 52289), a very high affinity radioligand for studying nicotinic acetylcholine receptors (nAChRs) by positron‐emission tomography, was synthesized through Kryptofix 222 assist

Synthesis of 6-chloro-3-((2-(S)-azetidin

Synthesis of 6-chloro-3-((2-(S)-azetidinyl)methoxy)-5-(2-[18F]fluoropyridin-4-yl)pyridine ([18F]NIDA 522131), a novel potential radioligand for studying extrathalamic nicotinic acetylcholine receptors by PET

✍ Yi Zhang; Andrew G. Horti 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 99 KB

## Abstract 6‐Chloro‐3‐((2‐(__S__)‐azetidinyl)methoxy)‐5‐(2‐[^18^F]fluoropyridin‐4‐yl)pyridine ([^18^F]NIDA 522131), a potential radioligand for studying extrathalamic nicotinic acetylcholine receptors by positron‐emission tomography, was synthesized via no‐carrier‐added nucleophilic [^18^F]fluorin