The aim of the present study was to investigate the effect of poly(acrylic acid)-cysteine (PAA-cysteine) exhibiting a molecular mass of 100 and 250 kDa and reduced glutathione (GSH) on the absorption of the P-glycoprotein (P-gp) and cytochrome P450 (CYP450) substrate paclitaxel in vitro and in vivo.
Evaluating the potential of polymer nanoparticles for oral delivery of paclitaxel in drug-resistant cancer
β Scribed by V. Bhardwaj; J. A. Plumb; J. Cassidy; M. N. V. Ravi Kumar
- Book ID
- 107678385
- Publisher
- Springer Vienna
- Year
- 2010
- Tongue
- English
- Weight
- 174 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1868-6958
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