Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis
β Scribed by Pfeifer, S; Perez-Andres, M; Ludwig, H; Sahota, S S; Zojer, N
- Book ID
- 109887494
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 254 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0887-6924
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The idiotypic structures of the myeloma protein might be regarded as tumor-specific antigens. The present study was designed to map T-cell epitopes of the idiotypic myeloma protein to prove the existence of naturally occurring majorhistocompatibility-complex-dependent idiotype (peptide)specific T ce
## Abstract The number of plasma cells in the lamina propria of the gut has been assessed in patients with multiple myeloma and other Bβcell neoplasms. The total number of these plasma cells was reduced in most patients with myelomatosis and oneβthird of patients with lymphoplasmacytoid tumours. Th