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Evaluating substrate specificity of glutathione peroxidase mimic by molecular dynamics simulations and kinetics

✍ Scribed by Shao-Wu Lv; Qing-Chuan Zheng; Ying Mu; Xiao-Guang Wang; Yue-Tong Ji; Gui-Min Luo; Jun-Qiu Liu; Jia-Cong Shen

Book ID
106389010
Publisher
Springer Netherlands
Year
2007
Tongue
English
Weight
294 KB
Volume
60
Category
Article
ISSN
0923-0750

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## Abstract The development of compounds to regulate the activation of the complement system in non‐primate species is of profound interest because it can provide models for human diseases. The peptide compstatin inhibits protein C3 in primate mammals and is a potential therapeutic agent against un