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Evaluating Rare Variants in Complex Disorders Using Next-Generation Sequencing

✍ Scribed by Ezewudo, Matthew; Zwick, Michael E.


Book ID
120660916
Publisher
Springer
Year
2013
Tongue
English
Weight
211 KB
Volume
15
Category
Article
ISSN
1523-3812

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Recent advances in next-generation sequencing technologies make it affordable to search for rare and functional variants for common complex diseases systematically. We investigated strategies for enriching rare variants in the samples selected for sequencing so as to optimize the power for their dis