𝔖 Bobbio Scriptorium
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EUROCVD-15

✍ Scribed by C. Vahlas


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
329 KB
Volume
12
Category
Article
ISSN
0948-1907

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15-Cyano-12-oxopentadecano-15-lactone was synthesized in 59% total yield starting from 2nitrocyclododecanone by Michael addition to acrylaldehyde, followed by reaction with trimethylsilylcyanide, hydrolysis, ring-expansion, and Nef reaction. A two-step, one-pot synthesis of intermediate 2hydroxy-4-(