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Eukaryotic chromosome replication requires both α and δ DNA polymerases

✍ Scribed by Julian Blow


Book ID
113288777
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
285 KB
Volume
5
Category
Article
ISSN
0168-9525

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DNA polymerases II (epsilon) and III (delta) are the only nuclear DNA polymerases known to possess an intrinsic 3'-->5' exonuclease in Saccharomyces cerevisiae. We have investigated the spontaneous mutator phenotypes of DNA polymerase delta and epsilon 3'-->5' exonuclease-deficient mutants, pol3-01