✦ LIBER ✦
Etude de l'addition nucleophile de quelques thiols sur les alcyn-1 ols-3; additions regio- et stereo-selectives du methyl-2 propanethiol-2.
✍ Scribed by Odile Ruel; Eric Guittet; Sylvestre Julia
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- French
- Weight
- 200 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The >/ 92 % regioselective nucleophilic trans-addition of 2-methyl-2-propanethiol to primary, secondary ond tertiary 1-alkyn-3-ols, catalyzed by 0,l equiv. of potassium hydroxide powder, affords good yields of anti-Markovnikoff products.
Pour confirmer la structure du compose (2, R1=R2=CH3,