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ETS transcription factors and their emerging roles in human cancer

✍ Scribed by Arun Seth; Dennis K. Watson

Book ID
116428720
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
280 KB
Volume
41
Category
Article
ISSN
0959-8049

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The PEA3 group of transcription factors belongs to the ets family and is composed of 3 known members, PEA3, ERM and ER81, which are more than 95% identical within the DNAbinding ETS domain and exhibit 50% aa identity overall. Recently, transgenic mice bearing the c-erbB-2/neu oncogene have been show