𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Etretinate may work where acitretin fails

✍ Scribed by T.O. BLEIKER; J.F. BOURKE; R.A.C. GRAHAM-BROWN; P.E. HUTCHINSON

Book ID
104458539
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
875 KB
Volume
136
Category
Article
ISSN
0007-0963

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✦ Synopsis

Acitretin (Ro 10-1670, Neotigason), a second-generation monoaromatic retinoid, is the main acid derivative and active metabolite of etretinate (Ro 10-9359, Tigason). Three patients who were unresponsive to treatment with acitretin but who responded to etretinate are reported. Twenty-nine patients in the U.K. are currently receiving etretinate on a named-patient basis. Possible explanations for the functional discrepancy between the two drugs are discussed.

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## Abstract This study sought for national characteristics that moderate the individual‐level relationship between job characteristics and job satisfaction. Data from two distinct questionnaire surveys administered to 107,292 employees in 49 countries was analyzed by employing multilevel modeling.