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Etoposide resistance in MCF-7 breast cancer cell line is marked by multiple mechanisms

✍ Scribed by Alpsoy, Aktan; Yasa, Seda; Gündüz, Ufuk


Book ID
121681571
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
614 KB
Volume
68
Category
Article
ISSN
0753-3322

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Annamycin (Ann) is a highly lipophilic anthracycline antibiotic that has been shown to circumvent MDR-1 both in vitro and in vivo. A liposomal formulation of Ann is currently in phase I clinical trials. The multidrug resistance-associated protein (MRP) has been found to be over-expressed in some hum