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Etiology of polydipsia and polyuria in rats with septal lesions

✍ Scribed by Joel F. Lubar; Barry A. Boyce; Carl F. Schaefer

Book ID
118961607
Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
403 KB
Volume
3
Category
Article
ISSN
0031-9384

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It has been proposed that lithium acts by inhibiting inositol monophosphatase, thereby lowering tissue inositol levels. We therefore studied inositol effects on a prominent lithium side-effect, polyuria-polydipsia, in rats and in humans. Rats were treated with daily injections i.p. LiCl for 14 days