๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Etiology, biology, and epidemiology of ovarian cancer

โœ Scribed by Trudy R. Baker; M. Steven Piver

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
571 KB
Volume
10
Category
Article
ISSN
8756-0437

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โœฆ Synopsis

Epithelial ovarian cancer kills more women per year than all other gynecologic cancers combined. Pregnancy, oral contraceptive use, and tuba1 ligation decrease the risk of the disease, whereas risk is increased for women whose family history is consistent with one of the familial ovarian cancer syndromes. Several theories have been postulated concerning the etiology of ovarian cancer, including the incessant ovulation theory and that based on the model of hypergonadotropic hypogonadism. Chromosomal abnormalities and allele losses have been described in ovarian cancers. Involvement of oncogenes and tumor suppressor genes has been investigated as well. Genetic linkage studies are ongoing in families whose history is consistent with one of the familial ovarian cancer syndromes. @ 1994 WiIey-Liss. Inc.

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