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Ethylene glycol poisoning treated by intravenous 4-methylpyrazole

✍ Scribed by Hantson, P.; Hantson, P.; Mahieu, P.

Book ID
113019364
Publisher
Springer
Year
1998
Tongue
English
Weight
458 KB
Volume
24
Category
Article
ISSN
1432-1238

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4-methylpyrazole (4-MP) was administered IV during haemodialysis of two ethylene glycol-intoxicated patients with anuric renal failure. The plasma 4-MP concentration decreased after each pass through the dialyser, indicating its dialysability in humans. In these two cases, the extraction coefficient