Ethyl brevifolin carboxylate from Flueggea microcarpa
β Scribed by Hugo E. Gottlieb; Sandeep Kumar; Mahendra Sahai; Anil B. Ray
- Book ID
- 103335606
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 462 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0031-9422
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Lithium enolates derived from the title esters show high diastereoface selectivity in their reactions with chiral aldehydes. The resulting 2,2-dithioaldols are desulfurized in good yield with Ni28-H2 (EtOH, 20Β°C). With this mild desulfurization protocol, complete retention of stereochemical integrit