Ethyl 3- and 5-Triflyloxy-1H-pyrazole-4-carboxylates in the Synthesis of Condensed Pyrazoles by Pd-Catalysed Cross-Coupling Reactions
✍ Scribed by Eglė Arbačiauskienė; Gytė Vilkauskaitė; Algirdas Šačkus; Wolfgang Holzer
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 626 KB
- Volume
- 2011
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Reactions of ethyl 3‐[(__E__)‐(dimethylamino)methylidene]pyruvate (**3**) and 3‐[(dimethylamino)methyl‐idene]‐2‐oxosuccinate (**4**) with hydrazine monohydrochloride (**5a**) and (hetero)arylhydrazines (**5b‐i**) afforded, regioselectively, 1‐substituted ethyl 1__H__‐pyrazole‐5‐carboxyl
## Abstract The 1__H__‐pyrazole‐3‐carboxylic acid **2**, obtained from the furan‐2,3‐dione **1** and __N__‐Benzylidene‐__N__'‐(3‐nitrophenyl) hydrazine, was converted via reactions of its acid chloride **3** with various alcohols or N‐nucleo‐philes into the corresponding ester or amide derivatives