Ethnic differences in risk and prognosis factors for breast cancer

✍ Scribed by Miguel A. Sanchez

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 158 KB
• Volume: 77
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(19960201)77:3<593::aid-cncr27>3.0.co;2-z

✦ Synopsis

provide little or no support of his concept. These include 1 ) the 1969 AFIP Fascicle on Tumors of the Peripheral Nervous System by Harkin and Reed,g wherein the term cellular schwannoma was used to denote a benign schwannoma, one cellular, exhibiting pleomorphism, both Antoni-A and B tissue, and only rare mitoses. An analogy to ancient schwannomatu was drawn, and the prognosis was stated to be that of ordinary schwannoma;

2. the 1993 supplement to the AFIP Fascicle wherein Reed and Harkin do not mention cellular schwannoma but do state that it is not the intention of the term "malignant schwannoma" to imply a relationship to benign schwannoma;" 3) an article by Sordillo et a1.l' that comments upon low grade "malignant schwannoma" but does not mention cellular schwannoma; and finally 4) a 1986 article summarizing the Mayo Clinic experience with malignant schwannoma wherein caution was advised with regard to acceptance of cellular schwannoma as an entirely benign lesion until such time as more than the 11 cases were published.' '

In summary, no peer review article in the past 25 years supports the notion'that tumors conforming to the definition of cellular schwannoma are anything but benign tumors. Their importance lies in the fact that their lack of recognition by the unwary results in a malignant diagnosis and needlessly aggressive treatment.