Ethnic differences in expression of the dysregulated proteins in uterine leiomyomata
โ Scribed by Wei, J.-J.
- Book ID
- 111926917
- Publisher
- Oxford University Press
- Year
- 2005
- Tongue
- English
- Weight
- 671 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0268-1161
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Uterine leiomyomata are the most common pelvic tumors in women and are the indication for more than 200.000 hysterectomies annually in the United States. Rearrangement of chromosome I2 in bands q 14-q I 5 is characteristic of uterine leiomyomata and other benign mesenchymal tumors, and we identified
Estrogens have an important function in the natural history of uterine leiomyomata. The human estrogen receptor beta gene (ESR2) has been identified recently and mapped to 14q22-24, a region frequently rearranged in uterine leiomyomata and other benign tumors, including pulmonary chondroid hamartoma