Ethical aspects of cardiopulmonary-cerebral resuscitation research depend on the perceptions of the individual concerned. Comments by a clinician, a legal scholar, and a philosopher on a variety of related issues broaden our understanding of this controversial topic.
Ethical aspects of research into the etiology of autism
β Scribed by Chen, Donna T. ;Miller, Franklin G. ;Rosenstein, Donald L.
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 98 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1080-4013
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Advances in understanding autism and other developmental neuropsychiatric disorders will come from an integration of various research strategies including phenomenologic, functional neuroimaging, and pharmacologic methods, as well as epidemiologic approaches aimed at identifying genetic and environmental risk factors. The highly heritable nature of autism makes it scientifically valuable to involve parents and siblings as research participants. However, many studies on autism pose ethical challenges because they do not offer the prospect of direct benefit to subjects. In this article, we present an inβdepth ethical analysis of current nontherapeutic research strategies that are common in autism research. The ethical analysis applies a proposed ethical framework for evaluating clinical research focusing on seven ethical requirements: (1) social or scientific value, (2) scientific validity, (3) fair subject selection, (4) favorable riskβbenefit ratio, (5) independent review, (6) informed consent, and (7) respect for potential and enrolled research participants. Β© 2003 WileyβLiss, Inc. MRDD Research Reviews 2003;9:48β53.
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