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Ethanol potentiation of hypoxic hepatocyte injury: role of alterations of intracellular Na+ homeostasis

✍ Scribed by R. Carini; M.G. De Cesaris; M. Parola; E. Albano

Book ID
118568818
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
163 KB
Volume
28
Category
Article
ISSN
0168-8278

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The mechanisms of hepatocyte injury caused by exogenous superoxide were investigated with the use of cultured rat hepatocytes. Cell viability, cytosolic free calcium concentration and cell surface structure were observed. Superoxide was produced by adding hypoxanthine and xanthine ozcidase to the bu