Effects of the putative antidepressant,
β
Wayne A. Cass; Marilyn N. Friedema; John F. DeBernardis; Daniel J. Kerkman; Greg
π
Article
π
1995
π
John Wiley and Sons
π
English
β 832 KB
ABT 200 [(RR,SS)-3-phenyl-l-~l',2',3',4'-tetrahydro-5',6'-methylenedioxy-1'-naphthalenyl-methyl]-pyrrolidine methanesulfonate] is a potent alpha2-adrenoceptor antagonist (Ki = 1.2 nM) with modest norepinephrine uptake-blocking activity (ICs0 = 841 nM) that is currently under clinical evaluation as a