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Ethanol Inhibits Acetate Metabolism in Rat Hepatocytes

✍ Scribed by Knudsen, Charlotte T. ;Quistorff, Bjørn ;Grunnet, Niels

Book ID
114802246
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
320 KB
Volume
76
Category
Article
ISSN
0901-9928

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Cocaine remains a widely abused illicit substance in our society. Cocaine hepatotoxicity has been linked to cocaine metabolism. Cocaine can undergo hydrolytic inactivation via plasma and hepatic esterases or it can be N-oxidized by cytochrome P-450 and FAD-containing monooxygenases. Ethanol is frequ