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Ethanol induced notochord and spinal cord duplications in the embryo of the zebrafish,Brachydanio rerio

✍ Scribed by Laale, Hans W.

Publisher: John Wiley and Sons
Year: 1971
Tongue: English
Weight: 883 KB
Volume: 177
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1401770107

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✦ Synopsis

Abstract

Embryos of Brachydanio rerio, stage 10 (Hisaoka and Battle, '58) were exposed for 24 hours to graded concentrations of ethanol from 1 to 3%. Developmental abnormalities included defects of the eye, i.e., approximation, confluence and fusion of the optic cups mid‐ventrally; as well as duplications of notochord and spinal cord. Duplication of the spinal cord in the hind brain region has not been reported previously. The duplicatory effects are discussed and a mechanism of duplication by infolding roof plate material is proposed.

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Reversible developmental arrest in the embryo of the zebrafish,Brachydanio rerio

✍ Laale, Hans W. ;McCallion, David J. 📂 Article 📅 1968 🏛 John Wiley and Sons 🌐 English ⚖ 978 KB

Zebrafish embryos at six developmental stages were exposed to the supernatant of homogenates of zebrafish embryos, 5-day chick embryos and 9mm frog larvae. Extracts of embryos bring about developmental arrest of the zebrafish embryo at stages 17-18. The effect is reversible. Arrested embryos returne