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Ethanol-Induced Liver Injury: Potential Roles for Egr-1

✍ Scribed by M T. Pritchard; L E. Nagy


Book ID
110087043
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
84 KB
Volume
29
Category
Article
ISSN
0145-6008

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We previously reported a link between ethanol-induced elevation of homocysteine, endoplasmic reticulum (ER) stress, and alcoholic liver injury in the murine model of intragastric ethanol feeding. We studied the role of TNFalpha in this setting by using TNFR1 knockout mice (C57 BL/6). There was a 7.4