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Ethanol-induced injury in rat primary cortical astrocytes involves oxidative stress: effect of idebenone

✍ Scribed by Carolina Muscoli; Massimo Fresta; Venera Cardile; Maddalena Palumbo; Marcella Renis; Giovanni Puglisi; Donatella Paolino; Steven Nisticò; Domenicantonio Rotiroti; Vincenzo Mollace


Book ID
117472935
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
109 KB
Volume
329
Category
Article
ISSN
0304-3940

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The potential therapeutic advantages of the encapsulation of idebenone within pegylated liposomes were investigated in vitro on primary cortical astrocytes of rats. In particular, both the concentration-dependent effects and the therapeutic effectiveness toward excitotoxic injury, elicited by chroni