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Ethanol enhances erbB-mediated migration of human breast cancer cells in culture

โœ Scribed by Jia Luo; Michael W. Miller

Book ID
110235411
Publisher
Springer US
Year
2000
Tongue
English
Weight
109 KB
Volume
63
Category
Article
ISSN
0167-6806

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## Abstract Receptor tyrosine kinase activity is essential for erbB2 (HER2/__neu__) promotion of breast carcinogenesis, metastasis and therapeutic resistance. erbB2 kinase can be activated by dimerization with another erbB receptor, most of which bind ligands. Of these, the erbB2/erbB3 heterodimer