Ethanol and acetonitrile induces conformational changes in porcine pepsin at alkaline denatured state

Urea-induced conformational changes in c

Urea-induced conformational changes in cold- and heat-denatured states of a protein, Streptomyces subtilisin inhibitor

✍ Takashi Konno; Yuji O. Kamatari; Mikio Kataoka; Kazuyuki Akasaka 📂 Article 📅 2008 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 667 KB

## Abstract __Streptomyces__ subtilisin inhibitor (SSI) is known to exist in at least two distinct denatured states, cold‐denatured (D') and heat‐denatured (D) under acidic conditions. In the present work, we investigated the manner how increasing urea concentration from 0 to 8 M changes the polype