Eta-1 (Osteopontin): An Early Component
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Ashkar, S.
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Article
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2000
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American Association for the Advancement of Scienc
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English
β 843 KB
Cell-mediated (type-1) immunity is necessary for immune protection against most intracellular pathogens and, when excessive, can mediate organ-specific autoimmune destruction. Mice deficient in Eta-1 (also called osteopontin) gene expression have severely impaired type-1 immunity to viral infection