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ET-18-OCH3-induced cytotoxicity and DNA damage in rat astrocytes

✍ Scribed by Marcella Renis; Venera Cardile; Maddalena Palumbo; Alessandra Russo


Book ID
117563439
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
543 KB
Volume
18
Category
Article
ISSN
0736-5748

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The induction of cell death in leukemic HL-60 cells by the ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3phosphocholine (ET-18-OCH 3 ; edelfosine) followed the typical apoptotic changes in ultrastructural morphology, including blebbing, chromatin condensation, nuclear membrane breakdown and exte