Estrogen stimulates growth of mammary tumor cells ZR-75 without activation of S6 kinase and S6 phosphorylation : Difference from epidermal growth factor and α-transforming growth-factor-induced proliferation

Ascochlorin inhibits growth factor-induc

Ascochlorin inhibits growth factor-induced HIF-1α activation and tumor-angiogenesis through the suppression of EGFR/ERK/p70S6K signaling pathway in human cervical carcinoma cells

✍ Ji-Hak Jeong; Yun-Jeong Jeong; Hyun-Ji Cho; Jae-Moon Shin; Jeong-Han Kang; Kwan- 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 582 KB

## Abstract Ascochlorin, a non‐toxic prenylphenol compound derived from the fungus __Ascochyta viciae__, has been shown recently to have anti‐cancer effects on various human cancer cells. However, the precise molecular mechanism of this anti‐cancer activity remains to be elucidated. Here, we invest